Category Archives: 2021

Winter arrived in Uppsala a few weeks ago, with temperatures getting as low as -17 °C. This led to most of the shallower lakes freezing over. There was an insignificant snowfall during the cold period, most of the snow melted when the temperature rose to slightly over zero for a few days. The result was lakes with mirror-like ice, 20 cm thick. The temperature is now a few degrees below zero. It is a real paradise for skaters and others wishing to enjoy the ability to walk on water.

A trend in Sweden over the past couple of winters, fuelled by a need to get out during the periods of restrictions, is winter bathing. We, Bitte, her sister Annika and me, have joined the winter-bathers and have joined in the trend with an ambition to bathe at least once a month for the whole year. This ambition was fulfilled during the last weekend when we took a (in my case, very brief) plunge in a nearby lake.

I have to admit that, while there is a certain degree of trepidation before entering the water. Winter bathing is quite exhilarating. However, the production of adrenaline and various endorphins, which contribute to the feel-good effect of winter bathing, are coupled to a less endearing effect on the male members (pun/double entendre intentional) of the species.

We intend to continue in our endeavours to bathe, at least, once a month during the coming year. With that I wish you all a very merry Christmas, and a happy and prosperous new year.

Merry Chris tmas

The agonising wait for the results of the PET scan is over and the results were good news. The scan showed an absence of areas with uptake of the radioactive marker, which means that there is no tumour activity present in my brain tissue (there was no feedback as to the presence of other activity!). The next MRI will be in three months, but in the meantime, everything looks good, allowing us to celebrate with a glass of bubbly and to enjoy the rapidly approaching festive season.

We restarted the Optune (see: Make it work, https://wordpress.com/post/tvanellus.com/284) treatment, but this is causing a great deal of discomfort in the form of an itchy rash and extensive areas of blisters. Assuming that the benefit from this treatment approaches the expected limit through a monomolecular or exponential function, most of it will have already been gained. We have therefore, after weighing the discomfort experienced against limited increase in benefit, decided to take an extended break from the Optune treatment. The positive result of this decision is that I can let my hair grow again. How much is a question for the future.

Should I go for Chris 1976?

Mohican Chris?

or, perhaps be a bit more adventurous, Like Martyn Poliakoff, Professor of Green Chemistry, Nottingham?

Cast your vote in the comments section.

On the subject of hair, I am reminded of the first time that I performed in public, which was in 1975. With my brother, David, on cornet, a friend, Philip Ostle on drums and me on clarinet, we played “Aquarius” and “Good morning starshine” from the musical “Hair” to rapturous applauds. Most of the public were related to us, so they were not impartial. A more critical audience may have been a bit less generous.

I got the results of my latest MRI scan a couple of weeks ago. I followed a short period of worry about what they may, or may not, reveal. When they finally arrived in my medical file, we could read a load of technical details about uptake of contrast agents and a few other things and the conclusion that there were no new signs of cancer cells in my brain and that the region around the operation area was essentially unchanged.

Naturally this leads me to ask the question: “Does essentially unchanged mean yes there are some indications of change but too small to define? The answer is of course a definite maybe, or as seen in “The vicar of Dibley”

After a brief discussion we decided that a PET scan was in order. I went to the PET centre on Friday and was injected with a very small amount radioactively labelled methionine and then had some pictures taken with a very fancy and expensive camera, equipped with a cheap and nasty waste-paper bin.

After the scan, I avoided people, especially children and  on the expectant mothers, as I was in a radiative state = Shining.

So now, a few days later, I am patiently awaiting these results.  Hopefully there will be nothing to worry about, and we can get into the Christmas spirit (both metaphorically and literally). Christmas cake and puddings have been made and are happily marinating in the pantry.

More to follow.

While doing a postdoc in Sherbrooke, Quebec, I was invited to Rhode Island to give a seminar about my research. Bitte and I drove from Sherbrooke to Rhode Island, a journey of 550 km. Our car was a second-hand Renault 5. It did not have air conditioning, so with temperatures in excess of 30 °C and humidity close to 100 % it was a fairly sweaty journey. At that time, 1987, small cars were only just appearing on the North American market. Most people drove around in fuel consuming monsters.

The seminar was really well received and afterwards we were treated to a barbeque at our hosts, Raymond and Marianne Panzica, with fresh lobster and swordfish as the main attractions. The lobster was so fresh that it was still crawling around in the kitchen when we arrived.

We had taken a few days off for the return journey. Marianne recommended Cape Cod as an absolute must for the trip and suggested a visit to Thompson’s Clam Bar for dinner.

We drove to Cape Cod and found a nice boarding house along the south coast. In the afternoon we took a drive up the east coast and enjoyed the beautiful scenery. We even tried a short swim in the Atlantic. It was a very short swim as the sea was very cold. This is because the waters off the east coast come from the Labrador current, which brings cold water from Newfoundland. In the evening we went for a swim off the south coast where the water was much warmer, coming from the north Atlantic current from the Caribbean. All very interesting, if you like that sort of thing.

A consequence of the meeting of these two currents is that there are a lot of nutrients in the water and therefore lots of fish, whales and other wildlife. This is probably why the whaling industry was established around Rhode Island and neighbouring Massachusetts.

Of all whaling stories, Moby Dick is probably the best known. Chapter 15 tells of how Captain Ahab and Queequag go ashore in Nantucket, just off the coast of Cape Cod, and enjoy the local clam chowder. It is for this local delicacy that we were recommended to visit Thompson’s Clam Bar.

Thompson’s Clam Bar had (after suffering serious damage due to hurricane Bob in 1991 and subsequent difficulties, the restaurant is no longer there), seating for over 500 guests, most of whom arrived by car. In order to avoid car-park chaos, the restaurant had a valet parking system. So, we arrived in our little Renault while all of the other guests arrived in Chevrolets, Buicks and other similar beasts. It must have been quite amusing to see our small car together with all of the others.

The food was fantastic as was the service and the general atmosphere. Having written this, I think that I will make a chowder later this week! Any leftovers will be stowed away😊 If you are also tempted to try your own chowder, I can recommend this presentation on Youtube, where the connection between Moby dick and clam chowder.

The book is a bit of a hard slog to get through, as is the 1956 film with Gregory Peck. However, there is a short version also available on youtube. We found this originally on a recording of 10 classics in 10 minutes, which is also worth looking up.

I hope you enjoyed this long and rambling post.

Finally, don’t forget to do as Captain Ahab did and “Stow the chowder!”

When I was a post-graduate student at the Biomedical Centre, BMC, in Uppsala, I shared an office with five other students. Each of us had a small desk, approximately 1 m wide, with panels on either side. My desk tended to overflow with lab notes and scientific articles – and a few other things as well.

Every now and then, the administrative supervisor would visit us on a safety inspection. On one particular occasion, he came into our office and suggested that my desk was so cluttered with paper that it posed a serious fire risk. He suggested that an overflowing and untidy desk reflects on the contents of my mind. I replied: “I assume that your desk is empty!” This he happily confirmed and continued with his inspection.

My desk was the cause of concern on another occasion. At the time, I was programme director at MASE-laboratories and we were, together with BioAgri, expecting a visit from the King of Sweden. A couple of days before the visit, the security police dropped by to ensure that everything was suitably presentable for the royal entourage. The police officer insisted that my desk should be tidied before the visit, and was not impressed by my suggestion that His Royal Highness would benefit more from seeing things as they are in real life. On the day of the visit, my door was kept closed so that the King was denied seeing the secrets that were hidden behind. I kept a low profile at the back of the room.

We recently returned from a glorious week at a training camp in Monte Gordo, Portugal. There, we enjoyed fantastic sunrises, morning jogs along the beach, various training sessions and really great food. The only cloud on the horizon was the approaching MRI-scan which took place today.

The scan itself is not a problem, but what it may reveal is a bit of a concern. I am confident that the results will be fine, as I have not shown any signs of quirkiness – other than those that have been with me for most of my life.

The scan today was fairly routine. I arrived at the hospital on time, and after a short interview about my current health status was told to put on a hospital shirt instead of the clothes that I had on. I was allowed to keep my underpants! During the scan I had to lie on a stretcher with my head strapped firmly in place. I had a set of sound insulating headphones to protect me from the noise of the scanner and to provide some musical distraction during the scan. The staff must have remembered me from previous visits, as they included “You’ll never walk alone” in the play list. I was quite moved as the song is about hope for a better future.

Cycling home from the hospital felt good. The sun was shining, the cold autumnal air was clean and crisp, and I had “You’ll never walk alone” ringing in my ears.

A few years ago, we (colleagues at work) were considering starting a research programme based on the use of smart materials. I needed to investigate the most interesting topics and figure out where the frontiers of the current research were at. As part of this effort, I enrolled in a conference in Busan, South Korea. We (Bitte joined me for the trip, the first time in over 30 years), flew, suitably compensating for green-house-gasses, to Seoul, and took the high-speed train from there to Busan. The train journey was very smooth, despite travelling at over 300 kmh.

We stayed at the Lotte Hotel, which was very nice and, apparently like all international Lotte hotels, includes a replica of the Trevi Fountain in Rome.

One thing that I found less pleasing was the call sign used by the lifts. This was the first bar of Clair de Lune, by Claude Debusy, a piece of music that I particularly like. Every time the lift arrived, it was greeted by the “Pling-pling-plong”. After a few times in the lift, I feared that I would never be able to listen to Clair de Lune again.

However:

I attended the 2020 AAAS meeting in Seattle, just before the pandemic restrictions were brought into force. Every morning and evening, while walking to and from the conference centre (they mis-spelled it over there), I passed by the Steinway piano showroom. My stops to view the merchandise became a little longer each time I passed by. On about the tenth time passing by the showroom, I could no longer resist, I had to go in for a closer look. Prices ranged from about $8 000 for an upright model, to $200 000. The expensive models, which were not on display, cost considerably more.

The sales assistant asked if I would like to try any of the models on display. I explained that I do not play the piano, but that I appreciate the craftmanship involved in their production and the skill required to play. She offered to demonstrate one of the pianos and asked if there is any particular piece that I would like to hear. I chose a grand piano ($150 000) and requested – you guessed it. The sound was absolutely fantastic, and my liking for Clair de Lune was restored.

I am so glad that I ventured into the Steinway showroom. If you ever pass by a Steinway showroom, stop and enter. You won’t regret it.

By the way, the photo on the MR Blue Sky entry was from the Seattle trip.

It has now gone a little over one year since I became ill. The time since then has been a bit of a roller-coaster ride with good days and not-so-good days. Fortunately, most have been good days. The initial information was hard to take in. I could easily have quoted John McEnroe “You cannot be serious”. There I was, in the prime of life (60 is, after all, the new 30) being told that I have a life-threatening condition that will require surgery, radiation treatment, chemotherapy and some other stuff as well.

I quickly learnt about my condition, its’ consequences and treatment and came to terms with having to live with it. Being on sick leave is quite challenging. In the middle of a pandemic this is made worse by not being allowed to meet with friends and family as much as I would like. Coping with the isolation and constant tiredness has meant that a good deal of time has been spent in front of the television. The European football championships and Olympic games have been a great help.

One programme which caught my attention, normally, I would have avoided it, has been “Naked and afraid”, where a group of contestants are left alone (with a camera team, sound team and production team, and probably a team of expert advisors and medical support) with no food, clothing or equipment, in a wilderness where they try to survive for a period ranging from 21 to 60 days.

Being an American programme, all expressions of foul language are censored with a beep and all anatomical naughty bits (check the goodies series from the 1970s) are pixelated. For the same reason, I doubt that is any major risk to the participants due to possible litigation in the event of a lion attack or similar incident.

The interesting part of the series is to see how the participants use their knowledge and ingenuity to secure food, water, and safe accommodation. In general, the series looks at how different individuals react to and cope with being in a very demanding situation.

I relate to this series because I also feel exposed to unknown dangers in a similar way. Fortunately, I get to keep my clothes, with the exception of a pair of hospital underpants (see earlier blog), food and other luxuries. I also have access to a fantastic support crew comprising the nurses, doctors, technicians, physiotherapists and other hospital support staff. Finally, I have my family and friends, who despite not being there physically, have given me a huge amount of support and encouragement throughout this time.

Thanks to all of you. I will pay you back by sticking around and continuing to be as irritating as possible.

I went for an MR scan last week. It was fairly routine as I am not one of the claustrophobic types. I did have a slight issue concerning the vein catheter. I now have a multicoloured bruise on my arm.

After a few days of anxious waiting, I got to see the oncologist, who gave me the reassuring news that there have been no detectable tumour developments inside my head. So, we opened a bottle of bubbly in the evening and relaxed. It seems that I am coping quite well with the treatment and all that goes with it:

Surgery – done

Radiotherapy – done

Chemotherapy part 1 – done

Chemotherapy part 2 – done

Electromagnetic fields – ongoing

I have no picture to show the inside of my head. Instead, here is a photo that I took of the volcano, Mt Rainier, as I flew into Seattle a few years ago. A suitable caption should refer to the colours being a representation of the bruise on my arm and the blue sky as a sign of a bright future. Or simply a reference to the ELO song, “Mr Blue Sky”

Every year, between August 9 and 14, a shower of shooting stars, called the Perseids, can be seen in the night sky, providing that it is cloud free and that there is not too much light pollution. Tonight, being right in the middle of this period, and with the sky being free from clouds, Bitte and I sat out in the garden in our deck chairs, at about midnight, and watched for shooting stars. We were out for about 30 minutes, Bitte saw seven and I saw six, most of them were a bit dim, but a couple were quite spectacular. This kind of activity makes me wonder what the neighbours think of us!

The first time I saw the Perseids was at a summer camp in Scarborough in about 1975. I lay in a field on the side of a hill in complete isolation and darkness for a couple of hours and was enthralled by the display. Unfortunately, I could not convince anybody else to share the experience.

I remember a particular evening in August 1980, going to the pub with some college friends. I referred to my previous viewing of the Perseids and noted that the sky was particularly clear and that there would be a good chance of seeing some shooting stars if we could find a place dark enough. Light pollution is particularly problematic in central London. After some discussion we decided that the middle of Saint James’s park, not to be confused with St James’ park, which is where Newcastle United play their home football matches, was probably our best bet. We dispersed from the pub, having arranged to meet up in the park at midnight with cameras, tripods and a few bottles of beer and whisky. It was, in fact, very dark in the middle of the park, so cameras were set for long exposure photos and prepared to see the shooting stars. We even found some deck chairs that we set up and made ourselves comfortable in. After a short while, a park warden turned up wondering what we were doing. He shone his torch into all the cameras and ruined the photos. However, slightly amused, he accepted our explanation and charged us 10 pence rental each for the deck chairs. He turned a blind eye to the various bottles on display. At some stage, later that night, we dispersed to our different addresses in and around London, one interesting experience richer.